The Future of Pediatric Epilepsy Surgery Through a Genetic Lens - Takeaways - MDSpire

The Future of Pediatric Epilepsy Surgery Through a Genetic Lens

Epilepsy in children continues to be a large-scale medical issue in children, affecting approximately 4 in 1,000 children each year. Epilepsy is defined as having two unprovoked, nonfebrile seizures.

  • December 11, 2024

  • 4 min

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    Epilepsy affects approximately 4 in 1,000 children annually, with 30% developing treatment-resistant epilepsy.

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    Children with medically refractory epilepsy are referred to specialized pediatric surgery centers for evaluation.

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    Cortical dysplasia is the most common condition treated in pediatric epilepsy surgery, with success rates of 50-80%.

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    Research highlights the importance of the PI3K-AKT-mTOR pathway in cortical dysplasia and its impact on epilepsy.

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    mTOR inhibitors show promise as a treatment for children with cortical dysplasia and catastrophic epilepsy.

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The Future of Pediatric Epilepsy Surgery Through a Genetic Lens

  • December 11, 2024

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