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1
Post-transplant diabetes mellitus (PTDM) affects 7–39% of kidney transplant recipients and worsens cardiovascular and allograft outcomes.
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2
PTDM shares features with type 2 diabetes but is influenced by immunosuppressive therapy, including calcineurin inhibitors and corticosteroids.
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3
Risk factors for PTDM include advanced age, ethnicity, pre-transplant dysglycemia, and certain infections, requiring careful patient stratification.
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4
Diagnosis of PTDM relies on OGTT, with HbA1c being less reliable in the early post-transplant period due to confounding factors.
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5
Management strategies for PTDM include personalized immunosuppression, lifestyle interventions, and emerging therapies like SGLT2 inhibitors.
