Beyond surgery: bladder preservation and the role of systemic treatment in localised muscle-invasive bladder cancer - Takeaways - MDSpire

Beyond surgery: bladder preservation and the role of systemic treatment in localised muscle-invasive bladder cancer

  • By

  • Martin Swinton

  • Aarani Devi

  • Yee Pei Song

  • Peter Hoskin

  • Ananya Choudhury

  • April 4, 2024

  • 0 min

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  • 1

    Radical cystectomy has been the standard treatment for muscle-invasive bladder cancer, but bladder-sparing approaches are now considered equivalent in disease control.

  • 2

    Trimodality therapy combines transurethral resection, radiotherapy, and radiosensitisers, showing improved outcomes compared to radiotherapy alone.

  • 3

    Retrospective analyses indicate that trimodality therapy offers equivalent metastasis-free survival and overall survival compared to radical cystectomy.

  • 4

    Advancements in radiotherapy techniques, such as hypofractionation and image-guided methods, enhance treatment efficacy while reducing toxicity.

  • 5

    The integration of MR imaging with radiotherapy delivery may allow for more precise targeting of tumors, potentially improving patient outcomes.

Original Source(s)

Beyond surgery: bladder preservation and the role of systemic treatment in localised muscle-invasive bladder cancer

  • by Martin Swinton, Aarani Devi, Yee Pei Song, Peter Hoskin, Ananya Choudhury

  • April 4, 2024

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