Efficacy of different nerve block techniques with liposomal bupivacaine for postoperative analgesia in patients undergoing single-port video-assisted thoracoscopic partial lung resection - Takeaways - MDSpire
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Comparative Analysis of Nerve Block Techniques Utilizing Liposomal Bupivacaine for Postoperative Pain Management in Patients Undergoing Uniportal Video-Assisted Thoracoscopic Lung Resection

  • By

  • Ying Zhang

  • Dongke Liang

  • Guofeng Liu

  • Yangsi Huang

  • Haiping Zhong

  • Nuo Yang

  • Yu Zhong

  • Yanhua Chen

  • June 17, 2026

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  • 1

    The study compared the efficacy of liposomal bupivacaine in thoracic paravertebral blockade and intercostal nerve blockade for postoperative pain management.

  • 2

    Sixty elective surgery patients were randomized to receive either TPVB or INB, with no significant differences in postoperative pain scores observed.

  • 3

    Both techniques resulted in low pain scores throughout the 72-hour postoperative period, with no significant differences in opioid consumption or rescue analgesia.

  • 4

    Long-term assessments showed no significant differences in chronic pain scores between the two groups at 1, 3, and 6 months postoperatively.

  • 5

    The trial did not establish equivalence between TPVB and INB, and the absolute analgesic efficacy of each technique remains undetermined.

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