Retinal connections to migraine - Takeaways - MDSpire

Retinal connections to migraine

  • By

  • Michal Fila

  • Jan Krekora

  • Jarosław Drożdż

  • Kai Kaarniranta

  • Janusz Blasiak

  • July 2, 2026

  • 0 min

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  • 1

    This review examines associations between migraine and retinal disorders, focusing on retinal migraine, age-related macular degeneration (AMD), and photophobia.

  • 2

    Retinal migraine is rare and poorly characterized, with insufficient data to support mechanistic conclusions regarding its pathophysiology.

  • 3

    Epidemiological studies suggest individuals with migraine may have a higher risk of developing neovascular AMD, indicating possible shared pathogenic pathways.

  • 4

    Photophobia, retinal artery occlusion, and changes in retinal nerve fiber layer thickness are reported more frequently in migraine patients than in controls.

  • 5

    Further studies are needed to clarify the significance of retinal alterations in migraine and whether they contribute to its pathophysiology.

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