Impact of red blood cell transfusion and transfusion strategies on clinical outcomes in extremely low gestational age neonates

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The study analyzed 545 extremely low gestational age neonates to assess the impact of red blood cell transfusion practices on clinical outcomes.
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Increased transfusion numbers were linked to a higher risk of bronchopulmonary dysplasia and lower survival without severe complications.
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A restrictive transfusion strategy resulted in fewer transfusions without increasing the risk of major adverse outcomes in ELGANs.
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Transfusion number was not significantly associated with severe retinopathy of prematurity or necrotizing enterocolitis.
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The findings support the implementation of restrictive transfusion practices in clinical settings for extremely low gestational age infants.

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