Association between bisphenol exposure and polycystic ovary syndrome risk: an integrated systematic review and meta-analysis - Takeaways - MDSpire

Association between bisphenol exposure and polycystic ovary syndrome risk: an integrated systematic review and meta-analysis

  • By

  • Zongying Gui

  • Huizhen Lin

  • Chuhan Wang

  • Yingsha Yao

  • June 11, 2026

  • 0 min

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  • 1

    The systematic review and meta-analysis evaluated 17 studies involving 3,010 women to assess the link between bisphenol exposure and PCOS risk.

  • 2

    Significant positive associations were found between PCOS risk and serum BPA, urinary BPA, and serum BPS, indicating potential endocrine disruption.

  • 3

    High heterogeneity was observed for BPA studies, while BPS studies showed no heterogeneity, suggesting variability in BPA's impact on PCOS.

  • 4

    The findings highlight the need for regulatory policies to reduce bisphenol exposure and integrate biomonitoring in PCOS management.

  • 5

    Addressing bisphenol exposure may provide new preventive and therapeutic strategies for managing PCOS effectively.

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