Lung- and diaphragm-protective mechanical ventilation in acute respiratory distress syndrome - Takeaways - MDSpire

Lung- and diaphragm-protective mechanical ventilation in acute respiratory distress syndrome

  • By

  • Glauco M. Plens

  • Idunn S. Morris

  • Richard Greendyk

  • Andrea Castellví-Font

  • Annemijn H. Jonkman

  • Domenico L. Grieco

  • Glasiele C. Alcala

  • Jose Dianti

  • Marcelo Britto Passos Amato

  • Martin Dres

  • Shailesh Bihari

  • Robinder G. Khemani

  • Laurent Brochard

  • Taiga Itagaki

  • Ewan C. Goligher

  • July 7, 2026

  • 0 min

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  • 1

    Patients with acute respiratory distress syndrome are at increased risk of lung and diaphragm injury during mechanical ventilation.

  • 2

    Lung-protective ventilation strategies aim to minimize ventilator-induced lung injury and improve clinical outcomes.

  • 3

    Diaphragm injury during mechanical ventilation can lead to ventilator-induced diaphragm dysfunction affecting over half of patients.

  • 4

    Overassistance and underassistance during mechanical ventilation can both contribute to diaphragm myotrauma.

  • 5

    Emerging lung- and diaphragm-protective ventilation strategies integrate gas exchange, lung stress limitation, and safe spontaneous breathing.

Original Source(s)

Lung- and diaphragm-protective mechanical ventilation in acute respiratory distress syndrome

  • by Glauco M. Plens, Idunn S. Morris, Richard Greendyk, Andrea Castellví-Font, Annemijn H. Jonkman, Domenico L. Grieco, Glasiele C. Alcala, Jose Dianti, Marcelo Britto Passos Amato, Martin Dres, Shailesh Bihari, Robinder G. Khemani, Laurent Brochard, Taiga Itagaki, Ewan C. Goligher

  • July 7, 2026

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