Characteristics of Human Metapneumovirus Infection Compared to Respiratory Syncytial Virus and Influenza Infections in Adults Hospitalized for Influenza-Like Illness in France, 2012–2022 - Takeaways - MDSpire

Characteristics of Human Metapneumovirus Infection Compared to Respiratory Syncytial Virus and Influenza Infections in Adults Hospitalized for Influenza-Like Illness in France, 2012–2022

  • By

  • Paul Loubet

  • Salomé Guitton

  • Simon Rolland

  • Louise H Lefrancois

  • Liem Binh Luong Nguyen

  • Philippe Vanhems

  • Fabrice Laine

  • Florence Galtier

  • Xavier Duval

  • Bruno Lina

  • Martine Valette

  • Giséle Lagathu

  • Vincent Foulongne

  • Nadira Houhou-Fidhou

  • Anne Sophie L’Honneur

  • Fabrice Carrat

  • Laurence Meyer

  • Christine Durier

  • Odile Launay

  • for the FLUVAC Study Group

  • July 16, 2025

  • 0 min

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  • 1

    The study analyzed 3620 hospitalized adults with influenza-like illness, identifying infections from hMPV, FLUV, and RSV.

  • 2

    Human metapneumovirus (hMPV) was detected in 5% of patients, while influenza viruses accounted for 42% and respiratory syncytial virus for 7%.

  • 3

    Patients with hMPV were more likely to develop complications, particularly acute heart failure, compared to those with influenza.

  • 4

    The in-hospital death rate was similar across hMPV, FLUV, and RSV groups, ranging from 4% to 5%.

  • 5

    Hospitalized hMPV infections predominantly affected older adults with chronic conditions, leading to frequent cardiac and pulmonary complications.

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