Tricuspid Regurgitation and Impact of Surgical Valve Intervention in the Single Ventricle Reconstruction Trial - Takeaways - MDSpire

Tricuspid Regurgitation and Impact of Surgical Valve Intervention in the Single Ventricle Reconstruction Trial

  • By

  • J. F. Cnota

  • S. M. Chowdhury

  • A. Floh

  • R. Gongwer

  • B. H. Goot

  • J. P. Jacobs

  • M. A. Jolley

  • S. Kirmani

  • D. J. LaPar

  • J. C. Levine

  • A. B. Lewis

  • R. H. Pignatelli

  • C. Pizarro

  • T. C. Slesnick

  • T. Thorsson

  • F. Trachtenberg

  • D. T. Truong

  • J. W. Newburger

  • P. C. Frommelt

  • February 18, 2026

  • 0 min

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  • 1

    Tricuspid regurgitation (TR) is common in single right ventricle anomalies and negatively impacts survival and transplantation rates.

  • 2

    The Single Ventricle Reconstruction trial showed a 61% transplant-free survival rate at 6 years for infants undergoing the Norwood procedure.

  • 3

    Moderate or greater TR prior to the Norwood procedure was linked to worse transplant-free survival at 6 years of age.

  • 4

    Post-Norwood, the proportion of participants with > mild TR significantly increased and remained stable through age 6.

  • 5

    Echocardiographic assessments indicated that RV size and function were modestly better in patients with ≤ mild TR compared to those with > mild TR.

Original Source(s)

Tricuspid Regurgitation and Impact of Surgical Valve Intervention in the Single Ventricle Reconstruction Trial

  • by J. F. Cnota, S. M. Chowdhury, A. Floh, R. Gongwer, B. H. Goot, J. P. Jacobs, M. A. Jolley, S. Kirmani, D. J. LaPar, J. C. Levine, A. B. Lewis, R. H. Pignatelli, C. Pizarro, T. C. Slesnick, T. Thorsson, F. Trachtenberg, D. T. Truong, J. W. Newburger, P. C. Frommelt

  • February 18, 2026

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