Machine learning-based prediction of stone-free rate after retrograde intrarenal surgery for lower pole renal stones - Takeaways - MDSpire

Machine learning-based prediction of stone-free rate after retrograde intrarenal surgery for lower pole renal stones

  • By

  • Hsiang Ying Lee

  • Yu-Hung Tung

  • Jose Carlo Elises

  • Yen-Chun Wang

  • Vineet Gauhar

  • Sung Yong Cho

  • July 12, 2025

  • 0 min

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  • 1

    Lower pole stones (LPS) account for 25-35% of renal stones and present unique challenges for retrograde intrarenal surgery (RIRS).

  • 2

    The stone-free rate (SFR) for LPS remains lower than for stones in other locations due to anatomical challenges like acute infundibulopelvic angle.

  • 3

    Machine learning (ML) models were developed to predict SFR after RIRS by analyzing various patient and stone-related characteristics.

  • 4

    The study included 327 patients, with data split for model development and validation, ensuring generalizability of the results.

  • 5

    SHAP values were used to interpret feature importance in the ML model, highlighting factors positively or negatively correlated with stone-free status.

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