Impact of the Triglyceride-Glucose Index on Prognosis Following Endovascular Therapy for Acute Ischemic Stroke: Effect Modification by Collateral Circulation - Takeaways - MDSpire

Impact of the Triglyceride-Glucose Index on Prognosis Following Endovascular Therapy for Acute Ischemic Stroke: Effect Modification by Collateral Circulation

  • By

  • Wang, Yishu

  • Lei, Qinyu

  • Wang, Jiaqi

  • Lin, Yachao

  • Xu, Liguo

  • June 1, 2026

  • 0 min

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  • 1

    The triglyceride-glucose (TyG) index is an independent risk factor for poor functional outcomes after endovascular therapy in acute ischemic stroke patients.

  • 2

    A total of 209 patients were analyzed, with 30.6% experiencing poor functional outcomes defined by a modified Rankin Scale score greater than 2.

  • 3

    The TyG index was significantly higher in patients with poor functional outcomes, alongside differences in sex, NIHSS score, and collateral circulation.

  • 4

    Collateral circulation significantly modifies the association between the TyG index and clinical outcomes, particularly in patients with poor collateral status.

  • 5

    The combined risk assessment model incorporating the TyG index demonstrated good predictive performance for poor outcomes at 90 days post-therapy.

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