Assessment of Venous Thrombus Characteristics in Renal Cell Carcinoma Patients Through Volumetric Computed Tomography First-Order Radiomic Features

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Renal cell carcinoma (RCC) has a 5-year overall survival rate of approximately 49%, which decreases with advanced stage and histopathological grade.
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Venous tumor thrombus (VTT) occurs in 5–15% of RCC cases and is associated with significantly reduced prognosis and survival rates.
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Current treatment for RCC with VTT includes radical nephrectomy with thrombectomy, which has high perioperative complication and mortality rates.
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This study aims to evaluate the use of CT first-order radiomic features to differentiate between friable and solid venous thrombi in RCC patients.
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Accurate preoperative characterization of thrombus consistency is crucial for surgical planning and can impact patient outcomes in RCC.

Bmc Cancer

by Paweł Kowal, Krzysztof Ratajczyk, Wiktor Bursiewicz, Maciej Trzciniecki, Karolina Marek-Bukowiec, Joanna Rogala, Yulian Mytsyk
February 4, 2026

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