Treatment of concomitant alopecia areata and systemic lupus erythematosus with ivarmacitinib: a case report and literature review - Takeaways - MDSpire
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Management of Concurrent Alopecia Areata and Systemic Lupus Erythematosus Using Ivarmacitinib: A Case Study and Review of Existing Literature

  • By

  • Wenjie Li

  • Zisheng Zhang

  • Ruoxin Huang

  • Yanni Mei

  • Zhengdong Shen

  • Yongliang Chu

  • September 14, 2026

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  • 1

    A 35-year-old woman with severe patchy hair loss was diagnosed with systemic lupus erythematosus after ineffective treatment for alopecia areata.

  • 2

    Ivarmacitinib, a selective JAK 1 inhibitor, led to marked clinical improvement in the patient's alopecia after previous treatments failed.

  • 3

    Trichoscopy findings after treatment included features consistent with both alopecia areata and lupus-associated alopecia.

  • 4

    The patient achieved an 80% reduction in the Severity of Alopecia Tool (SALT) score after 10 months of ivarmacitinib treatment.

  • 5

    This case highlights the diagnostic challenges of overlapping alopecic disorders and the potential role of JAK inhibitors in treatment.

Original Source(s)

Treatment of concomitant alopecia areata and systemic lupus erythematosus with ivarmacitinib: a case report and literature review

  • by Wenjie Li, Zisheng Zhang, Ruoxin Huang, Yanni Mei, Zhengdong Shen, Yongliang Chu

  • September 14, 2026

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