Systematic review and meta-analysis comparing surgical site infection in abdominal surgery between triclosan-coated and uncoated sutures

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Surgical site infections (SSIs) occur in 3–20% of abdominal surgeries and significantly impact patient outcomes and healthcare costs.
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Triclosan-coated sutures have bactericidal properties and aim to reduce SSIs, but may also contribute to bacterial resistance and skin irritation.
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Current guidelines from European and American Hernia Societies do not recommend triclosan-coated sutures due to insufficient evidence.
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This systematic review aims to evaluate the effect of triclosan-coated versus uncoated sutures on SSI incidence in abdominal surgery.
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The study will include randomized controlled trials and analyze data using a fixed-effects model to assess the odds of SSI.

Hernia

by Martijn Depuydt, Sarah Van Egmond, Stine Mette Petersen, Filip Muysoms, Nadia Henriksen, Eva Deerenberg
May 7, 2024

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