Osteoporosis Linked to Increased Dry AMD Risk - Takeaways - MDSpire

Osteoporosis Linked to Increased Dry AMD Risk

Genetic and pooled observational data suggest a unidirectional association, with elevated odds of dry age-related macular degeneration and a stronger signal in women.

  • By

  • Julie Greenbaum

  • February 24, 2026

  • 3 min

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  • 1

    Osteoporosis is linked to increased odds of dry age-related macular degeneration (AMD) in women, as shown in a meta-analysis.

  • 2

    Women with osteoporosis have 1.5 times the odds of overall AMD and 1.6 times the odds of early AMD, while no significant association was found in men.

  • 3

    The study utilized bidirectional Mendelian randomization and included data from nearly 484,000 patients to assess causality.

  • 4

    Only the association between osteoporosis and dry AMD met the adjusted significance threshold after Bonferroni correction.

  • 5

    Elderly women with osteoporosis should be considered a high-risk group for dry AMD in clinical practice, according to the researchers.

Original Source(s)

Osteoporosis Linked to Increased Dry AMD Risk

  • by Julie Greenbaum

  • February 24, 2026

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