Unilateral extrapedicular vs. bilateral transpedicular percutaneous kyphoplasty in osteoporotic vertebral compression fractures: an exploratory systematic review and meta-analysis - Takeaways - MDSpire

Unilateral extrapedicular vs. bilateral transpedicular percutaneous kyphoplasty in osteoporotic vertebral compression fractures: an exploratory systematic review and meta-analysis

  • By

  • Yihao Tao

  • Jingsong Cheng

  • Bo Wang

  • Hekai Shi

  • Wu Wang

  • Chao Yin

  • Sheng Chen

  • June 12, 2026

  • 0 min

Share

  • 1

    The study compares the unilateral extrapedicular approach (UEA) and bilateral transpedicular approach (BTA) in percutaneous kyphoplasty for osteoporotic vertebral compression fractures.

  • 2

    UEA-PKP and BTA-PKP showed similar efficacy in pain relief and vertebral height restoration, but UEA-PKP had advantages in operative duration and radiation exposure.

  • 3

    UEA-PKP resulted in lower cement volume and a reduced cement leakage rate compared to BTA-PKP, suggesting potential safety benefits.

  • 4

    The analysis included four studies with a total of 394 patients, highlighting the need for further research due to the limited number of studies available.

  • 5

    Findings indicate that UEA-PKP may offer safety advantages while maintaining efficacy, but results should be interpreted cautiously due to the exploratory nature of the research.

Original Source(s)

Unilateral extrapedicular vs. bilateral transpedicular percutaneous kyphoplasty in osteoporotic vertebral compression fractures: an exploratory systematic review and meta-analysis

  • by Yihao Tao, Jingsong Cheng, Bo Wang, Hekai Shi, Wu Wang, Chao Yin, Sheng Chen

  • June 12, 2026

Related Content

Elevating orthopedic documentation: a clinical audit of orthopaedic operative note quality against RCSE and BOA standards

Clinical outcomes of tibial cortex transverse transport versus antibiotic-loaded bone cement for Wagner grade 3–4 diabetic foot ulcers: a real-world retrospective cohort study

Modified Pemberton osteotomy for developmental dysplasia of the hip in children: a mid- to long-term follow-up study