Case Report: Benign colonic schwannoma with restricted diffusion mimicking malignancy - Takeaways - MDSpire

Case Report: Benign colonic schwannoma with restricted diffusion mimicking malignancy

  • By

  • Hao Zhu

  • Xiuya Cen

  • Chunchun Li

  • Deen Shi

  • Yongchou Li

  • Shitian Bao

  • Wei Weng

  • July 9, 2026

  • 0 min

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  • 1

    Colonic schwannoma is a rare benign tumor that can mimic malignancy due to imaging features like restricted diffusion and lymphadenopathy.

  • 2

    A 43-year-old woman presented with abdominal pain and a submucosal mass in the transverse colon, leading to a suspicion of malignancy.

  • 3

    MRI showed marked restricted diffusion and hyperintensity on diffusion-weighted imaging, suggesting a malignant process.

  • 4

    Postoperative histopathology confirmed a benign gastrointestinal schwannoma, with all lymph nodes showing reactive hyperplasia.

  • 5

    This case highlights the diagnostic challenge of distinguishing benign schwannoma from malignancy based on imaging alone.

Original Source(s)

Case Report: Benign colonic schwannoma with restricted diffusion mimicking malignancy

  • by Hao Zhu, Xiuya Cen, Chunchun Li, Deen Shi, Yongchou Li, Shitian Bao, Wei Weng

  • July 9, 2026

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