Reference values for PSA, PSA density, and MRI prostate volume in healthy German men - Takeaways - MDSpire
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Normal ranges for PSA, PSA density, and MRI-assessed prostate volume in healthy males from Germany

  • By

  • Maximilian Lindholz

  • Ivo G. Schoots

  • Robin Bülow

  • Patrick Asbach

  • Marc Kölln

  • Saskia Nolte

  • Salina Alaro

  • Richard Ruppel

  • Norbert Hosten

  • Tobias Penzkofer

  • Charlie A. Hamm

  • September 25, 2026

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  • 1

    The study establishes normative reference values for PSA, MRI-derived prostate volume, and PSA density in healthy males from Germany.

  • 2

    Prostate volume quantification via MRI is more accurate than traditional transrectal ultrasound methods, particularly for larger glands.

  • 3

    The research utilizes data from the Study of Health in Pomerania, focusing on men aged 20-79 without reported prostate diseases.

  • 4

    Participants were excluded if they had diagnoses of prostate cancer, lower urinary tract symptoms, or benign prostatic hyperplasia.

  • 5

    Automated segmentation for prostate volume measurement showed greater consistency compared to manual contouring methods.

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