Real-World Study on the Effectiveness and Breast Safety Analysis of Hormone Replacement Therapy During Menopause - Takeaways - MDSpire

Real-World Study on the Effectiveness and Breast Safety Analysis of Hormone Replacement Therapy During Menopause

  • By

  • Wang, Yingxia

  • Liu, Yaqin

  • Zeng, Jing

  • Wang, Mengyi

  • Li, Yuhuan

  • Wu, Yinglan

  • Gao, Jie

  • Chen, Xia

  • May 21, 2026

  • 0 min

Share

  • 1

    The study evaluated the effects of 24-month menopausal hormone therapy on bone mineral density and menopausal symptoms in postmenopausal women.

  • 2

    A total of 809 postmenopausal patients aged 40-60 years were enrolled from June 2021 to June 2022 for the study.

  • 3

    The prevalence of osteoporosis decreased significantly from 18.0% to 14.0% over the 24-month period (P < 0.001).

  • 4

    The mean Kuppermann score improved from 40.17 ± 6.04 at baseline to 11.38 ± 4.90 at 24 months (P < 0.001).

  • 5

    No significant changes were observed in breast density, volume, or the prevalence of calcifications or masses (all P > 0.05).

Original Source(s)

Real-World Study on the Effectiveness and Breast Safety Analysis of Hormone Replacement Therapy During Menopause

  • by Wang, Yingxia , Liu, Yaqin , Zeng, Jing , Wang, Mengyi , Li, Yuhuan , Wu, Yinglan , Gao, Jie , Chen, Xia

  • May 21, 2026

Related Content

Alzheimer Biomarkers Higher in Women

Researchers identify sex-specific differences in amyloid, tau, and brain structure during the seventh decade of life.

Mammography AI Spots Vascular Signals

Routine breast imaging offers opportunity for cardiovascular risk assessment.

Is 40 the Peak for Men's Sex Drive?

Estonian Biobank analysis of more than 67,000 adults challenges assumptions about age and desire, finding men's peak does not align with expected testosterone decline patterns.