Editorial: Immune-related biomarkers in skin and breast cancer: innovations in immunological diagnostics and therapies

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Cutaneous melanoma is a model for cancer immunology, showing sensitivity to immune checkpoint blockade despite challenges like resistance and toxicity.
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Non-melanoma skin cancers and breast cancer demonstrate the need for biomarkers that guide treatment decisions beyond mere associations.
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Breast cancer research is evolving towards integrating multiple biological factors, moving from single markers to complex immune stratification.
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Studies link metabolic and inflammatory programs to immune responses, suggesting blood-based markers can complement tissue biomarkers.
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Methodological integration of various data types is essential for credible immune stratification in breast cancer, impacting treatment decisions.

Frontiers In Immunology

by Domenico Mallardo, Margaret Ottaviano, Giuseppe Palmieri, Maria Teresa Melucci
June 17, 2026

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