Bayesian network meta-analysis comparing efficacy of surgical gastrojejunostomy, endoscopic stenting, and EUS-guided gastroenterostomy for malignant gastric outlet obstruction - Takeaways - MDSpire
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Bayesian Network Meta-Analysis of Surgical Gastrojejunostomy, Endoscopic Stenting, and EUS-Guided Gastroenterostomy for Malignant Gastric Outlet Obstruction

  • By

  • Zhixin Xie

  • Zhiyu Yan

  • Yunlu Feng

  • Aiming Yang

  • Wen Shi

  • Qiang Wang

  • October 16, 2026

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  • 1

    Malignant gastric outlet obstruction causes nausea, vomiting, poor oral intake, malnutrition, and reduced quality of life in patients with advanced malignancies.

  • 2

    Palliative options include surgical gastrojejunostomy, endoscopic stenting, and EUS-guided gastroenterostomy, each with trade-offs in durability, morbidity, and recovery.

  • 3

    The Bayesian network meta-analysis compared clinical success and reintervention, with adverse events, 30-day mortality, oral intake timing, hospital stay, and survival as secondary outcomes.

  • 4

    The analysis included 15 studies—7 randomized trials and 8 cohort studies—with 827 patients and evidence spanning all three treatment comparisons.

  • 5

    The primary network combined randomized and eligible comparative cohort evidence, with randomized-trial-only sensitivity analyses and study-design subgroup analyses assessing robustness.

Original Source(s)

Bayesian network meta-analysis comparing efficacy of surgical gastrojejunostomy, endoscopic stenting, and EUS-guided gastroenterostomy for malignant gastric outlet obstruction

  • by Zhixin Xie, Zhiyu Yan, Yunlu Feng, Aiming Yang, Wen Shi, Qiang Wang

  • October 16, 2026

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