A Decade-Long Real-World Cohort (2016-2025): Development of an Individualized Risk-Stratification Nomogram and Evaluation of Clinical Utility for Recurrent Respiratory Tract Infections in Children - Takeaways - MDSpire

A Decade-Long Real-World Cohort (2016-2025): Development of an Individualized Risk-Stratification Nomogram and Evaluation of Clinical Utility for Recurrent Respiratory Tract Infections in Children

  • By

  • Cai, Hehua

  • Li, Juan

  • Wang, Hui

  • April 14, 2026

  • 0 min

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  • 1

    Recurrent respiratory tract infections (RRTIs) significantly impact children's healthcare costs and quality of life.

  • 2

    A 10-year study identified independent predictors of RRTIs in 6,026 children, with 20.4% developing the condition.

  • 3

    Key predictors included allergy history, asthma, vitamin levels, birth weight, passive smoking, and hemoglobin levels.

  • 4

    A personalized nomogram was developed, demonstrating good discrimination and calibration for predicting RRTI risk.

  • 5

    The nomogram may enhance early risk stratification and preventive strategies in pediatric healthcare settings.

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