Neurologic Sequelae After Encephalitis Associated With Dengue Virus in Children - Takeaways - MDSpire

Neurologic Sequelae After Encephalitis Associated With Dengue Virus in Children

  • By

  • Neha Srivastava

  • Rakesh Mankal

  • Rohit Beniwal

  • Aman Agarwal

  • Umaer Alam

  • Ashok Kumar Pandey

  • Rajni Kant

  • Mahima Mittal

  • September 10, 2025

  • 0 min

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  • 1

    The study evaluated neurologic sequelae in pediatric patients with dengue-associated acute encephalitis syndrome (DEN-AES) from 2018 to 2019.

  • 2

    Out of 56 children studied, 39.3% exhibited neurologic sequelae, with severe disabilities noted in 6 cases and 1 postdischarge death.

  • 3

    Cognitive and behavioral impairments were the most common sequelae, affecting 37.5% of the children, with 5 requiring antiepileptic drugs.

  • 4

    The study highlights the need for early diagnosis, continuous follow-up, and rehabilitation policies in dengue-endemic regions.

  • 5

    Dengue virus was confirmed in cerebrospinal fluid, indicating its neurovirulence and association with increasing neurologic complications.

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