Frozen Section in Endometrial Care? - Takeaways - MDSpire
From the Journals

Frozen Section in Endometrial Care?

Systematic review examines intraoperative biopsy accuracy across endometrial pathologies and diagnostic settings.

  • By

  • Kathryn Wighton

  • May 12, 2026

  • 3 min

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  • 1

    FS biopsy shows high specificity but variable sensitivity.

  • 2

    Accuracy ranges widely; affected by tumor grade.

  • 3

    Sensitivity reported as 41% to 97%.

  • 4

    High-grade tumors and visible lesions yield better results.

  • 5

    FS biopsy should complement, not replace final histopathology.

  • 6

    Diagnostic performance is lower in complex atypical hyperplasia.

  • 7

    Majority of studies had low risk of bias.

  • 8

    FS biopsy is effective in confirming malignancy.

Original Source(s)

Frozen Section in Endometrial Care?

  • by Kathryn Wighton

  • May 12, 2026

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