Exploring the influencing factors of initial seizure time during modified electroconvulsive therapy in patients under 30 years old with mental disorders - Takeaways - MDSpire
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Identifying Factors Affecting Initial Seizure Duration in Patients Under 30 with Mental Disorders During Modified Electroconvulsive Therapy

  • By

  • Wanwen Li

  • Mingjian Cai

  • Xiaoli Sun

  • Huali Huang

  • Chao Ding

  • Shuang Fu

  • Changjiang Zhu

  • July 8, 2026

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  • 1

    The study included 287 patients under 30 years old with mental disorders undergoing modified electroconvulsive therapy (MECT).

  • 2

    Key factors influencing initial seizure duration during MECT were age, energy percentage, and etomidate dose, contributing over 79% of explanatory power.

  • 3

    The random forest classification model achieved an average precision of 76.9%, recall of 75.1%, and F1-score of 74.4% in predicting seizure duration.

  • 4

    Disease type, antiepileptic drug usage, and gender had minimal impact on seizure duration compared to age, energy percentage, and etomidate dose.

  • 5

    The study recommends setting the initial energy percentage to 1/3–2/5 of the patient's age to optimize seizure duration during MECT.

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