Steroid-related mechanisms in ocular health and disease: therapeutic effects, adverse events, and stress-related modulators. A narrative literature overview - Takeaways - MDSpire
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Mechanisms of Steroid Impact on Eye Health and Disease: Therapeutic Benefits, Side Effects, and Stress-Related Influencers - A Comprehensive Literature Review

  • By

  • Fabio Scarinci

  • Giulio Pocobelli

  • Francesca Romana Patacchioli

  • July 3, 2026

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  • 1

    The review examines the relationship between stress-related neuroendocrine dysregulation and ocular health, focusing on disease pathophysiology.

  • 2

    Thirty-five studies were included in the literature synthesis, highlighting the impact of glucocorticoids on ocular disease management.

  • 3

    Stress-related dysregulation is linked to ocular disorders like glaucoma and central serous chorioretinopathy.

  • 4

    Glucocorticoids are essential for treating inflammatory ocular diseases but can cause adverse effects such as glaucoma and cataracts.

  • 5

    The review emphasizes the need for personalized treatment approaches that consider stress as a modifiable factor in ocular health.

Original Source(s)

Steroid-related mechanisms in ocular health and disease: therapeutic effects, adverse events, and stress-related modulators. A narrative literature overview

  • by Fabio Scarinci, Giulio Pocobelli, Francesca Romana Patacchioli

  • July 3, 2026

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