Case Study: FAPI PET/CT Identifies Hidden Contralateral DCIS and Supraclavicular Metastasis, Informing Neoadjuvant Treatment in Synchronous Bilateral Breast Cancer

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FAPI PET/CT demonstrated superior sensitivity in detecting low-metabolic malignancies like DCIS compared to traditional FDG PET/CT.
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The patient initially diagnosed with unilateral inflammatory breast cancer was upstaged to synchronous bilateral breast cancer after FAPI PET/CT findings.
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FAPI PET/CT identified occult metastases in the left axillary and supraclavicular lymph nodes, which were missed by FDG PET/CT.
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Neoadjuvant chemotherapy led to a complete response in lymph nodes, as confirmed by follow-up FAPI PET/CT showing reduced uptake.
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This case underscores the importance of advanced imaging techniques like FAPI PET/CT in accurately staging and monitoring breast cancer.

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