Tpeak-Tend interval predicts VT inducibility in arrhythmogenic mitral valve prolapse syndrome - Takeaways - MDSpire

Tpeak-Tend interval predicts VT inducibility in arrhythmogenic mitral valve prolapse syndrome

  • By

  • Benjamin Rath

  • Julian Wolfes

  • Christian Ellermann

  • Fatih Güner

  • Felix Wegner

  • Julia Köbe

  • Florian Reinke

  • Gerrit Frommeyer

  • Lars Eckardt

  • April 15, 2026

  • 0 min

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  • 1

    Mitral valve prolapse (MVP) can lead to severe ventricular arrhythmias, including ventricular tachycardia (VT) and sudden cardiac death (SCD).

  • 2

    The study investigated Tpeak-Tend and Tpeak-Tend/QTc as predictors of VT inducibility in patients with suspected arrhythmogenic MVP (AMVP).

  • 3

    Prolonged Tpeak-Tend (> 90 ms) was significantly associated with increased ventricular arrhythmia inducibility during programmed ventricular stimulation.

  • 4

    In patients with prolonged Tpeak-Tend, 48.4% exhibited inducible VT/VF, compared to only 11.8% in those with normal Tpeak-Tend.

  • 5

    Previous syncope was the only known risk factor significantly correlated with ventricular arrhythmia inducibility in patients with AMVP.

Original Source(s)

Tpeak-Tend interval predicts VT inducibility in arrhythmogenic mitral valve prolapse syndrome

  • by Benjamin Rath, Julian Wolfes, Christian Ellermann, Fatih Güner, Felix Wegner, Julia Köbe, Florian Reinke, Gerrit Frommeyer, Lars Eckardt

  • April 15, 2026

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