Predictive value of early DCE and DSC perfusion MRI parameters for midterm clinical outcomes in lung cancer brain metastases treated with stereotactic radiosurgery - Takeaways - MDSpire

Predictive value of early DCE and DSC perfusion MRI parameters for midterm clinical outcomes in lung cancer brain metastases treated with stereotactic radiosurgery

  • By

  • Yunus Emre Senturk

  • Enes Muhammed Canturk

  • Ahmet Peker

  • Sabahattin Yüzkan

  • Yavuz Samancı

  • Selçuk Peker

  • May 23, 2025

  • 0 min

Share

  • 1

    Lung carcinoma accounts for 50% of all brain metastases, with poor prognosis despite advances in systemic treatment.

  • 2

    Stereotactic radiosurgery (SRS) is effective for local control of non-surgical tumors but predicting response remains challenging.

  • 3

    Dynamic contrast-enhanced (DCE) and dynamic susceptibility contrast (DSC) MRI parameters may help distinguish SRS responders from non-responders.

  • 4

    The study aims to evaluate early post-SRS DCE and DSC MRI parameters for predicting midterm clinical outcomes in lung cancer brain metastases.

  • 5

    Patients were classified as responders or non-responders based on midterm outcomes assessed at least six months after SRS.

Original Source(s)

Predictive value of early DCE and DSC perfusion MRI parameters for midterm clinical outcomes in lung cancer brain metastases treated with stereotactic radiosurgery

  • by Yunus Emre Senturk, Enes Muhammed Canturk, Ahmet Peker, Sabahattin Yüzkan, Yavuz Samancı, Selçuk Peker

  • May 23, 2025

Related Content

Targeted therapy combined with local consolidative surgery for oligometastatic stage IVA lung adenocarcinoma with CCDC6-RET fusion: a case report

Papillary thyroid carcinoma with brain and lung metastases: a case report

A pharmacodynamic study of rapid lactate metabolic modulation by intravenous L-arginine in brain metastases