Longitudinal changes in MMN and P3 during emotional processing in adolescents who engage in NSSI: a 12-week follow-up study - Takeaways - MDSpire

Longitudinal changes in MMN and P3 during emotional processing in adolescents who engage in NSSI: a 12-week follow-up study

  • By

  • Jianqiang Bi

  • Pei Liu

  • Zhenpeng Xue

  • Xiujuan Li

  • Qiang Xu

  • Yanbin Jia

  • Jianping Lu

  • June 10, 2026

  • 0 min

Share

  • 1

    A 12-week clinical intervention reduced self-injury ideation days and NSSI episode frequency in adolescents with NSSI.

  • 2

    The intervention decreased MMN amplitude to negative stimuli, indicating reduced automatic detection of negative emotional information.

  • 3

    P3 amplitude to negative stimuli increased post-intervention, suggesting enhanced controlled evaluation of negative emotions.

  • 4

    Responses to positive and neutral conditions remained stable, indicating specific effects of the intervention on negative stimuli.

  • 5

    MMN and P3 may serve as biomarkers for tracking intervention responses in adolescents with NSSI.

Original Source(s)

Longitudinal changes in MMN and P3 during emotional processing in adolescents who engage in NSSI: a 12-week follow-up study

  • by Jianqiang Bi, Pei Liu, Zhenpeng Xue, Xiujuan Li, Qiang Xu, Yanbin Jia, Jianping Lu

  • June 10, 2026

Related Content

Error in Abstract

  • June 2, 2026

Latent class profiles of psychiatric comorbidity among substance-affected Nigerian adolescents: a population-based analysis

Dual-Site aiTBS for Suicidal Ideation in Adolescents With Major Depressive Disorder: A Randomized Clinical