Perceived stress and depression among Chinese nurses: a cross-sectional mediation analysis of psychological flexibility and its components - Takeaways - MDSpire

Perceived stress and depression among Chinese nurses: a cross-sectional mediation analysis of psychological flexibility and its components

  • By

  • Zeyu Huang

  • Pan Diao

  • Tian Tian

  • Lei Yang

  • Xiaomei Li

  • May 28, 2026

  • 0 min

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  • 1

    Perceived stress significantly correlates with depression among nurses, with a correlation coefficient of r = 0.63.

  • 2

    Psychological flexibility partially mediates the relationship between perceived stress and depression in Chinese nurses.

  • 3

    Components of psychological flexibility, particularly acceptance and cognitive defusion, significantly contribute to the indirect association with depression.

  • 4

    Mindfulness and self-as-context did not show a significant indirect association with depression in the context of perceived stress.

  • 5

    The study highlights the importance of understanding psychological flexibility to inform interventions targeting depression among nurses.

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