Case report: Successful non-surgical management of massive isolated tricuspid Libman-Sacks endocarditis in a pregnant patient with SLE and secondary APS - Takeaways - MDSpire

Case report: Successful non-surgical management of massive isolated tricuspid Libman-Sacks endocarditis in a pregnant patient with SLE and secondary APS

  • By

  • Duan, Jiaoniu

  • Han, Lin

  • Zhao, Wenli

  • Zhang, Gailian

  • May 18, 2026

  • 0 min

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  • 1

    Isolated tricuspid valve Libman-Sacks endocarditis is rare and poses challenges during pregnancy, especially with severe thrombocytopenia.

  • 2

    A 21-year-old pregnant woman with systemic lupus erythematosus and secondary antiphospholipid syndrome presented with severe thrombocytopenia.

  • 3

    The patient declined surgery and opted for medical management, receiving intensive immunomodulatory therapy and anticoagulation.

  • 4

    The treatment led to platelet normalization, vegetation regression, and the successful delivery of a healthy infant.

  • 5

    This case highlights the potential for non-surgical management of extensive isolated tricuspid Libman-Sacks endocarditis in pregnant patients.

Original Source(s)

Case report: Successful non-surgical management of massive isolated tricuspid Libman-Sacks endocarditis in a pregnant patient with SLE and secondary APS

  • by Duan, Jiaoniu , Han, Lin , Zhao, Wenli , Zhang, Gailian

  • May 18, 2026

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