Plasma HERV-K envelopE RNA: a minimally invasive biomarker for lung adenocarcinoma detection and prognostic assessment in the context of conventional serum tumor markers - Takeaways - MDSpire

Plasma HERV-K envelopE RNA: a minimally invasive biomarker for lung adenocarcinoma detection and prognostic assessment in the context of conventional serum tumor markers

  • By

  • Fan Bu

  • Zi-Yan Jin

  • Zhi-Qiang Ling

  • July 1, 2026

  • 0 min

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  • 1

    Plasma HERV-K env mRNA was significantly upregulated in lung adenocarcinoma tissues compared to adjacent tissues.

  • 2

    HERV-K env mRNA levels were higher in lung adenocarcinoma than in lung squamous cell carcinoma.

  • 3

    Plasma HERV-K env mRNA showed strong correlation with tissue expression in both lung adenocarcinoma and lung squamous cell carcinoma.

  • 4

    High plasma HERV-K env mRNA levels were associated with poorer overall survival in lung adenocarcinoma patients.

  • 5

    The study suggests that plasma HERV-K env mRNA may serve as a non-invasive biomarker for diagnosing lung adenocarcinoma.

Original Source(s)

Plasma HERV-K envelopE RNA: a minimally invasive biomarker for lung adenocarcinoma detection and prognostic assessment in the context of conventional serum tumor markers

  • by Fan Bu, Zi-Yan Jin, Zhi-Qiang Ling

  • July 1, 2026

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