Incidence of Human Metapneumovirus Among Older Adults in 10 High-Income Countries: A Systematic Literature Review, Meta-analysis, and Modeling Study - Takeaways - MDSpire

Incidence of Human Metapneumovirus Among Older Adults in 10 High-Income Countries: A Systematic Literature Review, Meta-analysis, and Modeling Study

  • By

  • Jiali Lei

  • Catherine W Gillespie

  • Serena Santoni

  • Jam Suba

  • Niranjan Kanesa-thasan

  • Ajoke Sobanjo-ter Meulen

  • July 18, 2025

  • 0 min

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  • 1

    Human metapneumovirus (hMPV) significantly contributes to lower respiratory infections (LRI) in older adults across ten affluent nations.

  • 2

    The estimated incidence of hMPV-associated LRI in older adults ranged from 185.7 to 462.1 per 100,000 in 2019, varying by country.

  • 3

    A systematic literature review identified 21 studies, revealing that hMPV accounts for approximately 7.0% of LRI cases in adults aged ≥60 years.

  • 4

    hMPV infections can lead to severe complications, especially in older adults, yet the virus is often underdiagnosed in this population.

  • 5

    The study highlights the need for routine surveillance of hMPV to improve understanding and inform vaccine development strategies.

Original Source(s)

Incidence of Human Metapneumovirus Among Older Adults in 10 High-Income Countries: A Systematic Literature Review, Meta-analysis, and Modeling Study

  • by Jiali Lei, Catherine W Gillespie, Serena Santoni, Jam Suba, Niranjan Kanesa-thasan, Ajoke Sobanjo-ter Meulen

  • July 18, 2025

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