CT-derived myosteatosis as a predictor of postoperative outcomes in esophagogastric cancer surgery: a systematic review - Takeaways - MDSpire

CT-based assessment of myosteatosis as an indicator of surgical outcomes in esophagogastric cancer: a systematic review

  • By

  • Goran Rondovic

  • Momir Sarac

  • Ivan Lekovic

  • Nebojsa Maric

  • Sanja Sarac

  • Dusica Stamenkovic

  • Maja Stojanovic

  • Suzana Bojic

  • July 21, 2026

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  • 1

    Myosteatosis is associated with major postoperative complications in esophagogastric cancer surgery, with effect sizes ranging from 2 to 5.

  • 2

    Twenty-two studies with 6,733 patients were included in the systematic review evaluating CT-derived muscle quality parameters.

  • 3

    Muscle quality assessment via CT may provide better prognostic information than muscle quantity alone in predicting postoperative outcomes.

  • 4

    Methodological heterogeneity among studies limits comparability and clinical implementation of myosteatosis as a prognostic marker.

  • 5

    Future research should focus on standardizing muscle quality assessment and validating clinically accessible evaluation methods.

Original Source(s)

CT-derived myosteatosis as a predictor of postoperative outcomes in esophagogastric cancer surgery: a systematic review

  • by Goran Rondovic, Momir Sarac, Ivan Lekovic, Nebojsa Maric, Sanja Sarac, Dusica Stamenkovic, Maja Stojanovic, Suzana Bojic

  • July 21, 2026

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