Age-related changes in lens thickness in children aged 3-17 years and its association with myopia and ocular biological parameters: a cross-sectional and longitudinal study - Takeaways - MDSpire

Age-related changes in lens thickness in children aged 3-17 years and its association with myopia and ocular biological parameters: a cross-sectional and longitudinal study

  • By

  • Yuan, Qing

  • Fan, Kexin

  • Lu, Yan

  • April 14, 2026

  • 0 min

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  • 1

    The study analyzed lens thickness changes in children aged 3 to 17 years, involving 699 participants and 1,398 eyes.

  • 2

    Lens thickness exhibited a significant negative correlation with age, showing a triphasic pattern of decline, stabilization, and mild thickening.

  • 3

    Females had thicker lens thickness compared to males, with non-myopic children also exhibiting thicker lenses than myopic peers.

  • 4

    Longitudinal data indicated lens thickness decreased from ages 3 to 9, stabilized between 10 and 12, and increased from 13 to 17 years.

  • 5

    Age 10 is identified as a critical intervention window, with lens thickness serving as a potential biomarker for assessing pediatric refractive status.

Original Source(s)

Age-related changes in lens thickness in children aged 3-17 years and its association with myopia and ocular biological parameters: a cross-sectional and longitudinal study

  • by Yuan, Qing , Fan, Kexin , Lu, Yan

  • April 14, 2026

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