High-density lipoprotein cholesterol levels and prognosis in non-ischemic dilated cardiomyopathy - Takeaways - MDSpire

High-density lipoprotein cholesterol levels and prognosis in non-ischemic dilated cardiomyopathy

  • By

  • Chao Gong

  • Mengmeng Zhou

  • Shenzhen Gong

  • Chunxiao Liu

  • Jinying Zhang

  • June 26, 2026

  • 0 min

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  • 1

    The study investigated the association between HDL-C levels and long-term outcomes in patients with non-ischemic dilated cardiomyopathy (DCM).

  • 2

    Lower HDL-C levels were independently associated with increased risks of all-cause mortality and heart transplantation in DCM patients.

  • 3

    During a median follow-up of 35 months, 13.8% of patients experienced the primary endpoint of all-cause mortality or heart transplantation.

  • 4

    Kaplan-Meier analysis indicated that higher HDL-C levels correlated with significantly better event-free survival for both primary and secondary endpoints.

  • 5

    The association between HDL-C and clinical outcomes was partially attenuated after adjusting for pulmonary hypertension markers.

Original Source(s)

High-density lipoprotein cholesterol levels and prognosis in non-ischemic dilated cardiomyopathy

  • by Chao Gong, Mengmeng Zhou, Shenzhen Gong, Chunxiao Liu, Jinying Zhang

  • June 26, 2026

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