Mpox-Specific Neutralizing Antibodies up to 9 Months Following 1 or 2 Doses of Intradermal MVA-BN Vaccination in Sweden - Takeaways - MDSpire

Mpox-Specific Neutralizing Antibodies up to 9 Months Following 1 or 2 Doses of Intradermal MVA-BN Vaccination in Sweden

  • By

  • Carmen Espinosa-Gongora

  • Wanda Christ

  • Núria Mayola Danés

  • Claudia Eichler-Jonsson

  • Finn Filén

  • Elisabet Storgärd

  • Victor Westergren

  • Jonas Klingström

  • Sara Gredmark-Russ

  • Kari Johansen

  • Anna Mia Ekström

  • Klara Sondén

  • October 28, 2025

  • 0 min

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  • 1

    The study evaluated neutralizing antibody responses to the MVA-BN vaccine for mpox in a cohort of gay, bisexual, and other men who have sex with men in Sweden.

  • 2

    Neutralizing antibodies against the monkeypox virus significantly waned at 3 and 9 months post-vaccination, consistent with previous findings.

  • 3

    Participants received either one or two doses of the intradermal MVA-BN vaccine, with the second dose administered at least 28 days after the first.

  • 4

    The study highlights the need for further research on booster dosing and the development of immunological memory following vaccination.

  • 5

    Ethical approval was obtained, and all participants provided informed consent for their involvement in the study.

Original Source(s)

Mpox-Specific Neutralizing Antibodies up to 9 Months Following 1 or 2 Doses of Intradermal MVA-BN Vaccination in Sweden

  • by Carmen Espinosa-Gongora, Wanda Christ, Núria Mayola Danés, Claudia Eichler-Jonsson, Finn Filén, Elisabet Storgärd, Victor Westergren, Jonas Klingström, Sara Gredmark-Russ, Kari Johansen, Anna Mia Ekström, Klara Sondén

  • October 28, 2025

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