The difference in scotopic and photopic pupil responses: a potential indicator for long-term glycemic management - Takeaways - MDSpire
Coming Soon: Introducing MDSpire News. Learn more
Conexiant’s news site is now MDSpire News. Learn more

Variations in Pupil Responses to Low and High Light: A Possible Indicator for Long-Term Glycemic Control

  • By

  • Ye Li

  • Zeyu Pan

  • Qi Ren

  • Fan Shi

  • Pengxia Wan

  • June 17, 2026

Share

  • 1

    Diabetic patients exhibit significantly lower pupil diameter differences under varying light conditions compared to non-diabetic controls.

  • 2

    Quantitative pupillometry serves as a potential biomarker for assessing chronicity and autonomic neuropathy in diabetes.

  • 3

    The study included 362 participants, stratified into diabetic and non-diabetic cohorts, to evaluate pupillary responses.

  • 4

    Significant declines in pupil diameter differences were observed in diabetic patients with disease durations exceeding one year.

  • 5

    Receiver operating characteristic analysis indicated that pupil diameter difference can effectively identify established diabetes duration.

Original Source(s)

The difference in scotopic and photopic pupil responses: a potential indicator for long-term glycemic management

  • by Ye Li, Zeyu Pan, Qi Ren, Fan Shi, Pengxia Wan

  • June 17, 2026

Related Content

Factors associated with levothyroxine withdrawal and development of a prediction model in primary hypothyroidism

GLP-1 receptor agonists and psychiatric outcomes: a bibliometric analysis of research trends, thematic evolution, and collaboration networks

Can SGLT2 Inhibitors Affect Dementia?

A target trial emulation using Veterans Affairs electronic health records examined neuropsychiatric outcomes associated with SGLT2 inhibitor use.