Targeted transperineal biopsy of the prostate has limited additional benefit over background cores for larger MRI-identified tumors

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Transperineal biopsy offers advantages over transrectal methods, including reduced sepsis rates and improved sampling of anterior prostate tumors.
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MRI-targeted biopsies show higher detection rates for clinically significant prostate cancer compared to systematic biopsies.
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The study aims to identify when targeted biopsy cores provide significant benefits in cancer yield and grade stratification.
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Acquiring additional biopsy cores must balance the need for accurate diagnosis with the risks of increased morbidity and procedural complexity.
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The study highlights the importance of determining which MRI targets benefit most from targeted biopsy approaches.

World Journal Of Urology

by Tristan Barrett, Andrew J. Patterson, Brendan C. Koo, Karan Wadhwa, Anne Y. Warren, Andrew Doble, Vincent J. Gnanapragasam, Christof Kastner, Ferdia A. Gallagher
August 4, 2015

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