Anemia Tied to Higher Dementia Risk

Older adults with anemia showed elevated Alzheimer-related biomarkers and a higher hazard of dementia over follow-up

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Anemia is linked to a 66% increased risk of developing dementia in older adults, as shown in a cohort study of 2,282 participants.
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Higher levels of Alzheimer disease biomarkers, such as p-tau217 and neurofilament light chain, were associated with anemia.
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The risk of dementia was significantly higher when anemia co-occurred with elevated biomarker levels, particularly neurofilament light chain.
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Sex differences were noted, with stronger associations between anemia and dementia risk in men compared to women.
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Limitations of the study include the observational design and the measurement of hemoglobin and biomarkers only at baseline.

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