VCTE vs. histology in MASLD - Takeaways - MDSpire

VCTE vs. histology in MASLD

  • By

  • Doug Brunk

  • January 6, 2026

  • 2 min

Share

  • 1

    VCTE-based liver stiffness measurement (LSM) predicts liver-related outcomes in MASLD with accuracy comparable to liver biopsy.

  • 2

    The study analyzed 3,532 adults with MASLD, all of whom underwent both VCTE and liver biopsy at baseline.

  • 3

    During a median follow-up of 56.6 months, 126 patients (3.6%) developed liver-related events, primarily due to hepatic decompensation.

  • 4

    Five-year AUROC values for LSM and histology were nearly identical at 0.870 and 0.869, respectively.

  • 5

    LSM may serve as a practical alternative to histology for prognostic endpoints in clinical trials and risk stratification.

Original Source(s)

Related Content