The percentage abundance of sarcomatoid component has a prognostic role in grade 4 non-metastatic clear cell-renal carcinoma - Takeaways - MDSpire

The percentage abundance of sarcomatoid component has a prognostic role in grade 4 non-metastatic clear cell-renal carcinoma

  • By

  • Giuseppe Lucarelli

  • Francesco Lasorsa

  • Monica Rutigliano

  • Martina Milella

  • Marco Spilotros

  • Antonio d’Amati

  • Giuseppe Ingravallo

  • Felice Crocetto

  • Savio Domenico Pandolfo

  • Marco Fabiano

  • Matteo Ferro

  • Riccardo Autorino

  • Michele Battaglia

  • Pasquale Ditonno

  • April 23, 2025

  • 0 min

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  • 1

    Clear cell renal cell carcinoma (ccRCC) is the most common malignant histotype of renal cell carcinoma, accounting for a significant proportion of cases.

  • 2

    The presence of sarcomatoid features in ccRCC is associated with a highly aggressive phenotype and poor prognosis.

  • 3

    A study evaluated the prognostic impact of the percentage abundance of sarcomatoid features in patients with non-metastatic ccRCC.

  • 4

    Patients were categorized into low-sarcomatoid and high-sarcomatoid groups based on a 20% cut-off for sarcomatoid component abundance.

  • 5

    High-sarcomatoid patients exhibited larger tumor masses and worse cancer-specific survival compared to low-sarcomatoid patients.

Original Source(s)

The percentage abundance of sarcomatoid component has a prognostic role in grade 4 non-metastatic clear cell-renal carcinoma

  • by Giuseppe Lucarelli, Francesco Lasorsa, Monica Rutigliano, Martina Milella, Marco Spilotros, Antonio d’Amati, Giuseppe Ingravallo, Felice Crocetto, Savio Domenico Pandolfo, Marco Fabiano, Matteo Ferro, Riccardo Autorino, Michele Battaglia, Pasquale Ditonno

  • April 23, 2025

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