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1
EEG is a promising biomarker for Rett syndrome, but challenges include excessive artifacts and variable tolerance for longer recording sessions.
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2
An automated preprocessing pipeline was developed, retaining 95% of data compared to 28.4% with traditional methods, enhancing data quality for analysis.
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3
Stable power estimates from EEG recordings were achieved after 19-34 epochs, equating to approximately 76-136 seconds of artifact-free data.
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4
The study found no significant difference in stabilization thresholds between Rett syndrome and typically developing controls, though RTT showed higher signal instability.
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5
Approximately 3 minutes of raw resting-state EEG is sufficient for stable spectral features in children with Rett syndrome, supporting shorter acquisition times.
