Cognitive outcomes at preschool age in very preterm infants with normal MRI findings at term-equivalent age: identification of a vulnerable subgroup - Takeaways - MDSpire

Cognitive outcomes at preschool age in very preterm infants with normal MRI findings at term-equivalent age: identification of a vulnerable subgroup

  • By

  • Nina Volleritsch

  • Maria Sappler

  • Marlene Hammerl

  • Stephanie Mangesius

  • Ulrike Pupp Peglow

  • Elke Griesmaier

  • Ursula Kiechl-Kohlendorfer

  • Vera Neubauer

  • July 6, 2026

  • 0 min

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  • 1

    Very preterm infants with normal MRI findings at term-equivalent age showed a median IQ of 98, with 18.9% scoring below 85.

  • 2

    Male sex, preterm premature rupture of membranes, and early-onset sepsis were linked to adverse cognitive outcomes in this population.

  • 3

    Low maternal education and a non-German native language were significantly associated with lower cognitive performance.

  • 4

    Gestational age and birth weight did not show significant associations with cognitive outcomes in the studied cohort.

  • 5

    The study highlights the need for targeted developmental surveillance and follow-up for very preterm infants, even with normal MRI results.

Original Source(s)

Cognitive outcomes at preschool age in very preterm infants with normal MRI findings at term-equivalent age: identification of a vulnerable subgroup

  • by Nina Volleritsch, Maria Sappler, Marlene Hammerl, Stephanie Mangesius, Ulrike Pupp Peglow, Elke Griesmaier, Ursula Kiechl-Kohlendorfer, Vera Neubauer

  • July 6, 2026

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