A rare case of intramuscular granular cell tumor in the right thigh: case report and literature review - Takeaways - MDSpire

A rare case of intramuscular granular cell tumor in the right thigh: case report and literature review

  • By

  • Jue Hou

  • Yifeng Zheng

  • June 23, 2026

  • 0 min

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  • 1

    Granular cell tumor (GCT) is a rare soft tissue neoplasm, with granular cell tumor of the extremity (GCT-E) being even less common.

  • 2

    A 49-year-old male presented with a mass in the right thigh's vastus medialis muscle, which had enlarged over one year.

  • 3

    Multimodal imaging, including ultrasound, CT, MRI, and PET-CT, was utilized for diagnosis and surgical planning of the GCT-E.

  • 4

    Histopathological assessment confirmed the diagnosis of an atypical granular cell tumor after en bloc resection of the mass.

  • 5

    GCT-E is often misidentified as schwannoma, and multimodal imaging aids in delineating lesions and planning surgical strategies.

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