Fecal microbiota transplantation for patients with ulcerative colitis: a systematic review and meta-analysis of randomized control trials - Takeaways - MDSpire

Fecal microbiota transplantation for patients with ulcerative colitis: a systematic review and meta-analysis of randomized control trials

  • By

  • R. Gefen

  • J. Dourado

  • S. H. Emile

  • A. Wignakumar

  • P. Rogers

  • P. Aeschbacher

  • Z. Garoufalia

  • N. Horesh

  • S. D. Wexner

  • April 17, 2025

  • 0 min

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  • 1

    Fecal microbiota transplantation (FMT) may restore gut microbiota composition, potentially aiding in ulcerative colitis (UC) treatment.

  • 2

    This systematic review assessed randomized control trials comparing FMT with standard treatments for UC remission.

  • 3

    Factors influencing FMT efficacy include donor criteria, administration route, number of sessions, and concurrent medications.

  • 4

    The primary outcome measured was combined clinical and endoscopic remission, with secondary outcomes including Mayo score changes.

  • 5

    The study followed PRISMA guidelines and registered its protocol with PROSPERO, ensuring methodological transparency.

Original Source(s)

Fecal microbiota transplantation for patients with ulcerative colitis: a systematic review and meta-analysis of randomized control trials

  • by R. Gefen, J. Dourado, S. H. Emile, A. Wignakumar, P. Rogers, P. Aeschbacher, Z. Garoufalia, N. Horesh, S. D. Wexner

  • April 17, 2025

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