Patterns and risk factors of hyperkalemia recurrence among heart failure patients - Takeaways - MDSpire

Patterns and risk factors of hyperkalemia recurrence among heart failure patients

  • By

  • Christopher G. Rowan

  • Geraldine Francisco

  • Raymond C. Chang

  • K. Arnold Chan

  • Ravi Dhingra

  • June 11, 2026

  • 0 min

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  • 1

    The study analyzed hyperkalemia recurrence in 15,512 heart failure patients using EHR data from January 2019 to June 2023.

  • 2

    Recurrent hyperkalemia occurred in 49.5% of the full cohort and 37.3% of patients without chronic kidney disease within 12 months.

  • 3

    The mean number of hyperkalemia recurrences was 2.5 for the full cohort and 2.0 for the No-CKD subgroup, with mean K+ levels around 5.5 mmol/L.

  • 4

    Significant risk factors for hyperkalemia recurrence included a history of hyperkalemia, hypertension, advanced CKD, immunosuppressant therapy, and malignancy.

  • 5

    The study highlights the increasing frequency and decreasing time intervals between hyperkalemia recurrences in heart failure patients.

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