Differential Analysis of Homocysteine and Uric Acid Levels in Patients with Cognitive Impairment Due to Parkinson’s Disease and Post-Stroke Conditions - Takeaways - MDSpire

Differential Analysis of Homocysteine and Uric Acid Levels in Patients with Cognitive Impairment Due to Parkinson’s Disease and Post-Stroke Conditions

  • By

  • Jinbang Zhan

  • Wenfeng Zhang

  • Shuhua Guan

  • Yanan Liu

  • Xiaofen Lin

  • Jinli Yang

  • Weihua Yuan

  • Longyu Zhou

  • Gan Huang

  • April 24, 2026

  • 0 min

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  • 1

    The study compared homocysteine and uric acid levels in patients with cognitive impairment due to Parkinson's disease and post-stroke conditions.

  • 2

    Patients with Parkinson's disease and cognitive impairment had significantly higher homocysteine levels and lower uric acid levels than those with post-stroke cognitive impairment.

  • 3

    Elevated homocysteine levels negatively correlated with cognitive function, particularly in the Parkinson's disease group, but uric acid levels showed no significant association.

  • 4

    Low educational attainment, absence of hypertension, and lower uric acid levels were independently associated with Parkinson's disease cognitive impairment.

  • 5

    The findings suggest distinct metabolic profiles for Parkinson's disease and post-stroke cognitive impairment, highlighting the need for further prospective studies.

Original Source(s)

Differential Analysis of Homocysteine and Uric Acid Levels in Patients with Cognitive Impairment Due to Parkinson’s Disease and Post-Stroke Conditions

  • by Jinbang Zhan, Wenfeng Zhang, Shuhua Guan, Yanan Liu, Xiaofen Lin, Jinli Yang, Weihua Yuan, Longyu Zhou, Gan Huang

  • April 24, 2026

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